3,4-Dimethoxycinnamic acid
CAS No. 2316-26-9
3,4-Dimethoxycinnamic acid( O-Methylferulic acid )
Catalog No. M19332 CAS No. 2316-26-9
3, 4-Dimethoxycinnamic acid, previously identified in plasma after coffee consumption, was rapidly absorbed in the free form most likely by passive diffusion in the upper gastrointestinal tract.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name3,4-Dimethoxycinnamic acid
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NoteResearch use only, not for human use.
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Brief Description3, 4-Dimethoxycinnamic acid, previously identified in plasma after coffee consumption, was rapidly absorbed in the free form most likely by passive diffusion in the upper gastrointestinal tract.
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Description3, 4-Dimethoxycinnamic acid, previously identified in plasma after coffee consumption, was rapidly absorbed in the free form most likely by passive diffusion in the upper gastrointestinal tract.
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In Vitro3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 μM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells. 3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) inhibits the expression levels of Nox4 and p22phox in L-02 cells. 3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells.3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner.
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In Vivo——
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SynonymsO-Methylferulic acid
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2316-26-9
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Formula Weight208.21
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Molecular FormulaC11H12O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (240.14 mM)
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SMILESCOC1=C(C=C(C=C1)/C=C/C(=O)O)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Farrell TL,et al.Absorption of dimethoxycinnamic acid derivatives in vitro and pharmacokinetic profile in human plasma following coffee consumption. 2012 Sep;56(9):1413-23.
molnova catalog
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